The lesson of ivermectin: meta-analyses based on summary data alone are inherently unreliable
" Since the above primary studies were published, many hundreds of thousands of patients have been dosed with ivermectin, relying on an evidence base that has substantially evaporated under close scrutiny. …Relying on low-quality or questionable studies in the current global climate presents severe and immediate harms. …"
it’s brief and they miss some obvious points (made here on the Quillette forum) re meta-analysis that should have led anyone to consider the ivermectin meta-analysis dubious
edit: please recall that weinstain (and heather) said meta-analysis is superior evidence to eg RCT, so stupid